HCV Translational Research: Solving Complex Problems Through a Multidisciplinary Approach
"Dahari Lab is committed to the WHO goal of global HCV elimination"
At Dahari Lab, we believe solving complex problems is best achieved through a multidisciplinary approach. Our research often includes theoretical (modeling), experimental (cells and animal models) and clinical (patient-based) information to answer research questions. Prof. Susan Uprichard (who participated in the development of the first robust cell culture-based HCV infection system) and Harel Dahari have co-founded a Program for Experimental and Theoretical Modeling (PETM) at Stritch School of Medicine, to promote the interdisciplinary integration of mathematical modeling and experimental biology. Our translational research is undertaken with Prof. Scott Cotler (Director, Division of Hepatology) and partnerships with clinicians from the U.S. and abroad. It is through this research and partnerships that we apply our knowledge from basic biology and clinical trials to techniques and tools designed to improve health outcomes. Overall, the research undertaken often becomes the building blocks for other areas of research. This “Science for the sake of Science” is the first step in any interdisciplinary research. It forms the backbone that leads to work and discoveries that benefit people. This science can also guide or create a check and balance for organizations like the FDA, NIH or pharmaceutical companies. Not every experiment or clinical trial yields a positive result, but it continues to strengthen the foundational knowledge of the scientific community.