Modeling-based response-guided DAA therapy for chronic hepatitis C to identify individuals for shortening treatment duration

Ashish Goyal, Alex Churkin, Danny Barash, Scott J Cotler, Amir Shlomai, Ohad Etzion, Harel Dahari

OPEN FORUM INFECTIOUS DISEASES

March 2022

[Full Text, Pubmed]

Abstract

Shortening duration of direct-acting-antiviral therapy for chronic hepatitis C could provide cost-saving, reduce medications exposure and foster adherence and treatment completion in special populations. The current analysis indicates that measuring hepatitis C virus at baseline and on days 7 and 14 of therapy can identify patients for shortening therapy duration.